scbmtБИОМЕДИЦИНАJournal Biomed2074-59822713-0428Scientific center of biomedical technologies of Federal Medical and Biological Agency10.33647/2074-5982-16-2-60-67scbmt-1188Research ArticleМЕТОДЫ БИОМЕДИЦИНСКИХ ИССЛЕДОВАНИЙMETHODS OF BIOMEDICAL RESEARCHESБелки теплового шока. Свойства. Роль в адаптации. Методические подходы к определениюHeat Shock Proteins. Properties. Role in Adaptation. Methodological Approaches to DefinitionМаксимовичН. Е.MaksimovichN. Ye.

Максимович Наталия Евгеньевна, доктор медицинских наук, профессор

230009, Гродно, ул. Горького, д. 80

Nataliya Ye. Maksimovich, Dr. Sci. (Med.), Prof.

230009, Grodno, Gorkogo str., 80

mne@grsmu.byБоньЕ. И.BonE. I.

Бонь Елизавета Игоревна, кандидат биологических наук

230009, Гродно, ул. Горького, д. 80

Elizaveta I. Bon, Cand. Sci. (Biol.)

230009, Grodno, Gorkogo str., 80

asphodela@list.ruУО «Гродненский государственный медицинский университет»БеларусьGrodno State Medical UniversityBelarus202009062020026067Copyright © Максимович Н.Е., Бонь Е.И., 20202020Максимович Н.Е., Бонь Е.И.Maksimovich N.Y., Bon E.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.scbmt.ru/jour/article/view/1188

Цель данного обзора — обобщение и систематизация данных литературы о свойствах, роли в адаптации и методиках изучения в эксперименте белков теплового шока. Синтез белков теплового шока является универсальным ответом на стресс и играет важную роль в защите клеток от негативных воздействий. Белки теплового шока принимают большое участие в реализации фундаментальных клеточных процессов, и изменение их экспрессии может служить важным диагностическим маркером реакции клетки на повреждения.

The aim of this review article is to generalize and systematize literature data on the properties of heat shock proteins, as well as their role in adaptation processes and experimental methods of their investigation. The synthesis of heat shock proteins is a universal response to stress, which plays an important role in protecting cells from negative external impacts. Heat shock proteins participate in fundamental cellular processes. Altered expression of heat shock proteins can serve as an important diagnostic marker of cellular responses to damage.

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The authors declare that there are no conflicts of interest present.