scbmtБИОМЕДИЦИНАJournal Biomed2074-59822713-0428Scientific center of biomedical technologies of Federal Medical and Biological Agency10.33647/2074-5982-18-3-18-21scbmt-1403Research ArticleМЕТОДЫ И ТЕХНОЛОГИИ БИОМЕДИЦИНСКИХ ИССЛЕДОВАНИЙMETHODS AND TECHNOLOGIES OF BIOMEDICAL RESEARCHИзменения кишечной микробиоты мышей под воздействием ультразвукового стрессаChanges in the Gut Microbiota of Mice Under the Action of Ultrasonic-induced StressКарабановС. Ю.KarabanovS. Yu.

Карабанов Сергей Юрьевич - кандидат ветеринарных наук.

109316, Москва, ул. Талалихина, 26.

Sergey Yu. Karabanov - Cand. Sci. (Vet.), V.M. Gorbatov Federal Research Center for Food Systems of RAS.

109316, Moscow, Talalikhina Str., 26.

s.karabanov@fncps.ruКибиткинаА. А.KibitkinaA. A.

Кибиткина Анастасия Анатольевна.

109316, Москва, ул. Талалихина, 26.

Anastasiya A. Kibitkina.

109316, Moscow, Talalikhina Str., 26.

a.kibitkina@fncps.ruФГБНУ «Федеральный научный центр пищевых систем им. В.М. Горбатова» РАНРоссияV.M. Gorbatov Federal Research Center for Food Systems of RASRussian Federation2022161020221831821Copyright © Карабанов С.Ю., Кибиткина А.А., 20222022Карабанов С.Ю., Кибиткина А.А.Karabanov S.Y., Kibitkina A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.scbmt.ru/jour/article/view/1403

Изучено влияние ультразвукового стресса на состав кишечной микробиоты мышей линии C57BL/6. Показано, что воздействие такого вида стресса смещает состав кишечной микробиоты в сторону фирмикутов на уровне филума, на уровне семейства наблюдается повышение Lachnospiraceae на 67,43%, Rikenellaceae — на 39,29%, а также снижение Bacteroidaceae на 64,75%, Prevotellaceae — на 38,51%. Наибольшие изменения под воздействием стресса выявлены на уровне рода: из 28 идентифицированных родов значительные изменения фиксировали в 13.

The effect of ultrasound-induced stress on the gut microbiota composition of C57BL/6 mice was studied. Under the action of this type of stress, the gut microbiota composition shifts towards firmicutes at the phylum level. At the family level, an increase in Lachnospiraceae by 67.43%, Rikenellaceae by 39.29%, as well as a decrease in Bacteroidaceae by 64.75% and Prevotellaceae by 38.51%. is observed. The most prominent changes under the action of stress were revealed at the genus level: out of 28 identified genera, significant changes were recorded in 13.

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The authors declare that there are no conflicts of interest present.