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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">scbmt</journal-id><journal-title-group><journal-title xml:lang="ru">БИОМЕДИЦИНА</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Biomed</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5982</issn><issn pub-type="epub">2713-0428</issn><publisher><publisher-name>Scientific center of biomedical technologies of Federal Medical and Biological Agency</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33647/2074-5982-20-3-61-65</article-id><article-id custom-type="elpub" pub-id-type="custom">scbmt-1605</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РЕЛЕВАНТНОЕ И АЛЬТЕРНАТИВНОЕ БИОМОДЕЛИРОВАНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RELEVANT AND ALTERNATIVE BIOMODELLING</subject></subj-group></article-categories><title-group><article-title>Современные животные модели химиоиндуцированной периферической полинейропатии</article-title><trans-title-group xml:lang="en"><trans-title>Current Animal Models of Chemotherapy-Induced Peripheral Polyneuropathy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Приходько</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Prikhodko</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Приходько Вероника Александровна, к.б.н.</p><p>197376, Санкт-Петербург, ул. Профессора Попова, 14, лит. А</p><p>197376, Санкт-Петербург, ул. Академика Павлова, 12, лит. А</p></bio><bio xml:lang="en"><p>Veronika A. Prikhodko, Cand. Sci. (Biol.)</p><p>197376, Saint Petersburg, Professora Popova Str., 14, lit. A</p><p>197376, Saint Petersburg, Akademika Pavlova Str., 12, lit. A</p></bio><email xlink:type="simple">veronika.prihodko@pharminnotech.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Матузок</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Matuzok</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Матузок Татьяна Максимовна</p><p>197376, Санкт-Петербург, ул. Профессора Попова, 14, лит. А</p><p>197376, Санкт-Петербург, ул. Академика Павлова, 12, лит. А</p></bio><bio xml:lang="en"><p>Tatyana M. Matuzok</p><p>197376, Saint Petersburg, Professora Popova Str., 14, lit. A</p><p>197376, Saint Petersburg, Akademika Pavlova Str., 12, lit. A</p></bio><email xlink:type="simple">matuzok.tatyana@pharminnotech.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Оковитый</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Okovitiy</surname><given-names>S V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Оковитый Сергей Владимирович, д.м.н., проф.</p><p>197376, Санкт-Петербург, ул. Профессора Попова, 14, лит. А</p><p> </p></bio><bio xml:lang="en"><p>Sergey V. Okovitiy, Dr. Sci. (Med.), Prof., </p><p>197376, Saint Petersburg, Professora Popova Str., 14, lit. A</p></bio><email xlink:type="simple">sergey.okovity@pharminnotech.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный химико-фармацевтический университет» Минздрава России; ФГБУН «Институт мозга человека им. Н.П. Бехтеревой» РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia; N.P. Bechtereva Institute of the Human Brain of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный химико-фармацевтический университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>11</day><month>11</month><year>2024</year></pub-date><volume>20</volume><issue>3</issue><fpage>61</fpage><lpage>65</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Приходько В.А., Матузок Т.М., Оковитый С.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Приходько В.А., Матузок Т.М., Оковитый С.В.</copyright-holder><copyright-holder xml:lang="en">Prikhodko V.A., Matuzok T.M., Okovitiy S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.scbmt.ru/jour/article/view/1605">https://journal.scbmt.ru/jour/article/view/1605</self-uri><abstract><p>Химиоиндуцированная периферическая нейропатия (ХИПН) является частым осложнением противоопухолевой химиотерапии, с трудом поддающимся коррекции у значительной части пациентов. Настоящий обзор посвящён современным моделям ХИПН на грызунах с использованием противоопухолевых средств различных групп.</p></abstract><trans-abstract xml:lang="en"><p>Chemotherapy-induced peripheral neuropathy (CIPN) is a common complication of antineoplastic chemotherapy. In a large number of patients, this complication is highly persistent to treatment. The present review is focused on current rodent CIPN models using antineoplastic agents of different groups.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>химиоиндуцированная периферическая нейропатия</kwd><kwd>периферические полинейропатии</kwd><kwd>токсические полинейропатии</kwd><kwd>противоопухолевые средства</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chemotherapy-induced peripheral neuropathy</kwd><kwd>peripheral polyneuropathies</kwd><kwd>toxic neuropathies</kwd><kwd>antineoplastic agents</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Banach M., Juranek J.K., Zygulska A.L. Chemotherapy-induced neuropathies — a growing problem for patients and health care providers. Brain Behav. 2016;7(1):e00558. DOI: 10.1002/brb3.558</mixed-citation><mixed-citation xml:lang="en">Banach M., Juranek J.K., Zygulska A.L. 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