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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">scbmt</journal-id><journal-title-group><journal-title xml:lang="ru">БИОМЕДИЦИНА</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Biomed</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5982</issn><issn pub-type="epub">2713-0428</issn><publisher><publisher-name>Scientific center of biomedical technologies of Federal Medical and Biological Agency</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">scbmt-247</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group></article-categories><title-group><article-title>Значение гена раннего реагирования c-fos и продуктов его экспрессии в нейронах при различных воздействиях</article-title><trans-title-group xml:lang="en"><trans-title>The values of early response gene с-fos and products of its expression in neurons under different treatments</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецов</surname><given-names>С. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsov</surname><given-names>S. L.</given-names></name></name-alternatives><email xlink:type="simple">am-mma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Афанасьев</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Afanasyev</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">am-mma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ГБОУ ВПО Первый МГМУ имени И. М. Сеченова Минздравсоцразвития России, Москва<country>Россия</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>20</day><month>01</month><year>2020</year></pub-date><volume>1</volume><issue>1</issue><fpage>109</fpage><lpage>116</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кузнецов С.Л., Афанасьев М.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Кузнецов С.Л., Афанасьев М.А.</copyright-holder><copyright-holder xml:lang="en">Kuznetsov S.L., Afanasyev M.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.scbmt.ru/jour/article/view/247">https://journal.scbmt.ru/jour/article/view/247</self-uri><abstract><p>В статье обобщён материал исследований по изучению экспрессии гена раннего реагирования c-fos в клетках нервной системы и белков c-fos, синтез которых он инициирует в различных условиях эксперимента. Показано, в частности, участие гена и его продуктов в физиологических и патологических процессах, протекающих в отдельных структурах нервной системы.</p></abstract><trans-abstract xml:lang="en"><p>In article summariezes the material experimental studies on the early response gene с-fos in the cells of the nervous system and protein с-fos, which it initiates synthesis of variety experimental conditions. It is shown, in particular, the involvment of gene and its products in the physiological and pathological processes proceeding in the individual structures of nervous system.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гены раннего реагирования</kwd><kwd>мРНК c-fos</kwd><kwd>c-fos-белки</kwd><kwd>нейроапоптоз</kwd><kwd>early response genes</kwd><kwd>с-fos mRNA</kwd><kwd>с-fos proteins</kwd><kwd>neuroapoptosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Анохин К.В. Принципы и механизмы деятельности мозга человека. Л.: Наука. 1989. С. 191-192.</mixed-citation><mixed-citation xml:lang="en">Анохин К.В. Принципы и механизмы деятельности мозга человека. Л.: Наука. 1989. С. 191-192.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Афанасьев М.А. 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