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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">scbmt</journal-id><journal-title-group><journal-title xml:lang="ru">БИОМЕДИЦИНА</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Biomed</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5982</issn><issn pub-type="epub">2713-0428</issn><publisher><publisher-name>Scientific center of biomedical technologies of Federal Medical and Biological Agency</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">scbmt-693</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Фармакоэпидемиология бета-адреноблокаторов
у больных ишемической болезнью сердца
в сочетании с хронической обструктивной
болезнью лёгких и возможности небиволола
Pharmacoepidemiology beta-blockers in patients with
  coronary heart disease in combination with chronic
obstructive pulmonary disease and nebivolol capabilities</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гурова</surname><given-names>А. Ю.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чаплыгин</surname><given-names>А. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Свет</surname><given-names>А. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозова</surname><given-names>Т. Е.</given-names></name></name-alternatives><email xlink:type="simple">elmed@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цветкова</surname><given-names>О. А.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Первый МГМУ им. И.М.Сеченова, Москва
Контактная</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>13</day><month>02</month><year>2020</year></pub-date><volume>1</volume><issue>4</issue><fpage>73</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гурова А.Ю., Чаплыгин А.В., Свет А.В., Морозова Т.Е., Цветкова О.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Гурова А.Ю., Чаплыгин А.В., Свет А.В., Морозова Т.Е., Цветкова О.А.</copyright-holder><copyright-holder xml:lang="en">Гурова А.Ю., Чаплыгин А.В., Свет А.В., Морозова Т.Е., Цветкова О.А.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.scbmt.ru/jour/article/view/693">https://journal.scbmt.ru/jour/article/view/693</self-uri><abstract><p>Важным результатом работы является выявленная у больных ИБС в сочетании с ХОБЛ низкой привер-
женности к терапии бета-адреноблокаторами (БАБ). Несмотря на выбор преимущественно кардиоселектив-
ных БАБ, у большинства больных либо не достигаются целевые дозы препаратов, либо БАБ отменяются из-
за опасения усиления бронхообструкции. Средне-терапевтические дозы небиволола не оказывают влияния
на ОФВ1 и не ухудшают функциональных возможностей дыхательной системы при физической нагрузке.
An important result achieved is the low adherence to COPD therapy beta-blockers detected in patients
with coronary artery disease. Despite the selection of predominantly cardioselective beta blockers, in most
patients either the target doses of drugs are not reached, or the beta blockers have to be canceled due to fears
of strengthening the bronchial obstruction. Mid-therapeutic doses of nebivolol have no effect on FEV1 and do
not impair the functional possibilities of the respiratory system during physical exercise.</p></abstract><kwd-group xml:lang="ru"><kwd>бета-адреноблокаторы</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>хроническая обструктивная болезнь лёгких</kwd><kwd>beta-blockers</kwd><kwd>coronary heart disease</kwd><kwd>chronic obstructive pulmonary disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
