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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">scbmt</journal-id><journal-title-group><journal-title xml:lang="ru">БИОМЕДИЦИНА</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Biomed</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5982</issn><issn pub-type="epub">2713-0428</issn><publisher><publisher-name>Scientific center of biomedical technologies of Federal Medical and Biological Agency</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">scbmt-710</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Патогенетические особенности стенокардии
в зависимости от степени поражения коронарного
русла как одна из основ персонализации
фармакотерапии
Pathogenetic features of angina pectoris according to the
degree of coronary channel as a basis of personalization
                   pharmacotherapy</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ромащенко</surname><given-names>О. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кукес</surname><given-names>В. Г.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Третьяков</surname><given-names>А. Ю.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алфёров</surname><given-names>П. К.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузубова</surname><given-names>Л. И.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыкова</surname><given-names>Е. Г.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Грищенко</surname><given-names>Н. Д.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клочкова</surname><given-names>Г. Н.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ничикова</surname><given-names>Л. Н.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>elmed@yandex.ru</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>13</day><month>02</month><year>2020</year></pub-date><volume>1</volume><issue>4</issue><fpage>121</fpage><lpage>123</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ромащенко О.В., Кукес В.Г., Третьяков А.Ю., Алфёров П.К., Кузубова Л.И., Рыкова Е.Г., Грищенко Н.Д., Клочкова Г.Н., Ничикова Л.Н., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Ромащенко О.В., Кукес В.Г., Третьяков А.Ю., Алфёров П.К., Кузубова Л.И., Рыкова Е.Г., Грищенко Н.Д., Клочкова Г.Н., Ничикова Л.Н.</copyright-holder><copyright-holder xml:lang="en">Ромащенко О.В., Кукес В.Г., Третьяков А.Ю., Алфёров П.К., Кузубова Л.И., Рыкова Е.Г., Грищенко Н.Д., Клочкова Г.Н., Ничикова Л.Н.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.scbmt.ru/jour/article/view/710">https://journal.scbmt.ru/jour/article/view/710</self-uri><abstract><p>Изучались патогенетические особенности стенокардии напряжения в зависимости от степени по-
ражения коронарного русла у 36-ти пациентов. Полученные данные свидетельствуют о более тяжё-
лом клиническом состоянии пациентов с многососудистым поражением коронарного русла и их более
старшим возрастом. Нарушений локальной сократимости миокарда по данным эходопплерографии у
пациентов с поражением одного и двух сосудов не было обнаружено, а у пациентов с поражением трех
и более сосудов оно определялось в 64% случаев (p&lt;0,1).
We studied the pathogenetic features of angina, depending on the degree of coronary lesions in 36 patients.
The data indicate a more severe clinical condition of patients with multivessel coronary lesions and their older
age. Violations of local myocardial according ehodopplerografii in patients with lesions 1 and 2 vessels were
found, and patients with lesions of 3 or more vessels, it was determined in 64% (p&lt;0,1).</p></abstract><kwd-group xml:lang="ru"><kwd>поражение коронарного русла</kwd><kwd>персонализированная фармакотерапия</kwd><kwd>coronary artery lesion</kwd><kwd>personalized pharmacotherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
