scbmtБИОМЕДИЦИНАJournal Biomed2074-59822713-0428Scientific center of biomedical technologies of Federal Medical and Biological Agencyscbmt-904Research ArticleСтатьиОсобенности системы биотрансформации лекарственных средств в фетоплацентарном комплексеСоковаЕ. А.noemail@neicon.ruИнститут клинической фармакологи ФГУ «НЦЭСМП» Росздравнадзора, МоскваRussian Federation200813022020111425Copyright © Сокова Е.А., 20202020Сокова Е.А.Сокова Е.А.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.scbmt.ru/jour/article/view/904

В аналитическом обзоре представлены и обсуждаются молекулярные механизмы эволю ции экспрессии ферментов I и II фазы системы биотрансформации ксенобиотиков у плода и в плаценте. В настоящее время понимание и знание метаболизма лекарственных средств в материнско плацентарно плодном комплексе, факторов, оказывающих влияние на эти процессы, имеет первостепенное значение в оценке соотношения польза/риск примене ния лекарственных средств как для материнского организма, так и для плода на протяже нии всей беременности.

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The authors declare that there are no conflicts of interest present.