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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">scbmt</journal-id><journal-title-group><journal-title xml:lang="ru">БИОМЕДИЦИНА</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Biomed</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-5982</issn><issn pub-type="epub">2713-0428</issn><publisher><publisher-name>Scientific center of biomedical technologies of Federal Medical and Biological Agency</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">scbmt-963</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Снижение «изомерического балласта» и безопасность лекарств</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Байдак</surname><given-names>Д. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терещук</surname><given-names>Н. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цветков</surname><given-names>Д. Н.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гильдеева</surname><given-names>Г. Н.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Научный центр биомедицинских технологий РАМН, Москва</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ММА им. И.М. Сеченова, Москва</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2006</year></pub-date><pub-date pub-type="epub"><day>13</day><month>02</month><year>2020</year></pub-date><volume>1</volume><issue>2</issue><fpage>126</fpage><lpage>129</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Байдак Д.В., Терещук Н.В., Цветков Д.Н., Гильдеева Г.Н., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Байдак Д.В., Терещук Н.В., Цветков Д.Н., Гильдеева Г.Н.</copyright-holder><copyright-holder xml:lang="en">Байдак Д.В., Терещук Н.В., Цветков Д.Н., Гильдеева Г.Н.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.scbmt.ru/jour/article/view/963">https://journal.scbmt.ru/jour/article/view/963</self-uri><abstract><p>В статье проанализирована возможность снижения числа неблагоприятных побочных ре,
акций лекарств при применении их энантиомеров на примере трех репаратов: амлодипи,
на, клопидогреля и циклосерина.</p></abstract><kwd-group xml:lang="ru"><kwd>энантиомеры</kwd><kwd>изомерический балласт</kwd><kwd>рацемические смеси</kwd><kwd>конфор</kwd><kwd>меры</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Машковский М.Д. Лекарственные средства. М.: Медицина. Т. 2, с.381;382.</mixed-citation><mixed-citation xml:lang="en">Машковский М.Д. Лекарственные средства. М.: Медицина. Т. 2, с.381;382.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ajayi A.A, Adigun A.Q. Syncope following oral chloroquine administration in a hypertensive patient controlled on amlodipine. Br J Clin Pharmacol. 2002 Apr; 53(4): 404;5.</mixed-citation><mixed-citation xml:lang="en">Ajayi A.A, Adigun A.Q. 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