Study of the Antihypoxic Activity of a New Benzimidazole Derivative with Dicarboxylic Acid under Histotoxic Hypoxia
https://doi.org/10.33647/2074-5982-16-3-102-105
Abstract
The antihypoxic activity of a new benzimidazole derivative with dicarboxylic acid under histotoxic hypoxia was studied. It was established that the studied pharmacological agent at a dose of 25 mg/kg increases the life expectancy of animals by 2 times compared with the control group, 1.3 times compared to ethylthiobenzimidazole hydrochloride and 1.2 times compared to ethylmethylhydroxyperidine succinate.
About the Authors
Yu. D. Bolotina
Saint Petersburg State Chemical Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Yuliya D. Bolotina
197376, Saint Petersburg, Professora Popova str., 14
V. Ts. Bolotova
Saint Petersburg State Chemical Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Vera Ts. Bolotova, Cand. Sci. (Pharm.), Assoc. Prof.
197376, Saint Petersburg, Professora Popova str., 14
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Review
For citations:
Bolotina Yu.D., Bolotova V.Ts. Study of the Antihypoxic Activity of a New Benzimidazole Derivative with Dicarboxylic Acid under Histotoxic Hypoxia. Journal Biomed. 2020;16(3):102-105. (In Russ.) https://doi.org/10.33647/2074-5982-16-3-102-105
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