Bioelectrical impedance of the body in rats with monocrotaline-induced pulmonary hypertension
https://doi.org/10.33647/2074-5982-15-1-95-101
Abstract
Wistar rats with monocrotaline-induced pulmonary hypertension were investigated using bioelectrical impedance analysis. Monocrotaline-treated rats compared to sham-treated rats demonstrated significantly lower absolute values of such components of bioelectrical impedance as the reactive resistance (32.9±4.9 Ohm vs. 39.3±5.3 Ohm in the sham control, ρ=0.023) and the phase angle (7.1±0.6º vs. 8.2±0.6º in the sham control, ρ=0.002). The active resistance of the bioelectrical impedance of the lung showed a downward trend in rats having undergone monocrotaline treatment (with a significantly lower value at 150 kHz: 398.9±240.2 Ohm vs. 647.2±270.5 Ohm in the sham control, ρ=0.043). A decrease in the whole-body and pulmonary bioimpedance values under our experimental conditions is shown to result from accumulation of the whole-body or intrathoracic fluid and physiological changes in the tissues during the development of pulmonary arterial hypertension.
About the Authors
N. L. Kolomeyets
Komi Scientific Centre of the Ural Branch of the Russian Academy of Sciences
Russian Federation
Russian Federation
Cand. Sci. (Phys.- Math.),
167982, Syktyvkar, Kommunisticheskaya str., 24
O. V. Suslonova
Komi Scientific Centre of the Ural Branch of the Russian Academy of Sciences
Russian Federation
167982, Syktyvkar, Kommunisticheskaya str., 24
Russian Federation
167982, Syktyvkar, Kommunisticheskaya str., 24
S. L. Smirnova
Komi Scientific Centre of the Ural Branch of the Russian Academy of Sciences
Russian Federation
167982, Syktyvkar, Kommunisticheskaya str., 24
Russian Federation
167982, Syktyvkar, Kommunisticheskaya str., 24
I. M. Roshchevskaya
Pitirim Sorokin Syktyvkar State University
Russian Federation
Russian Federation
Dr. Sci. (Med.), Corresponding Member of the RAS,
167001, Syktyvkar, Octjabrskii prospect, 55
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Review
For citations:
Kolomeyets N.L., Suslonova O.V., Smirnova S.L., Roshchevskaya I.M. Bioelectrical impedance of the body in rats with monocrotaline-induced pulmonary hypertension. Journal Biomed. 2019;(1):95-101. (In Russ.) https://doi.org/10.33647/2074-5982-15-1-95-101
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