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In vitro determination of the release rate of selenoxanthene synthetic derivative from its soft dosage form

https://doi.org/10.33647/2713-0428-17-3E-28-31

Abstract

The release rate of Selenopyran, a selenoxanthene synthetic derivative, from 1% gel-cream was studied using a vertical diffusion cell. The experimental results showed that, on average, 77.5% of Selenopyran of the total amount is released from a soft-dosage form sample within 3 hours.

About the Authors

D. V. Zayats
PHARMA-SEVER
Russian Federation

164501, Severodvinsk, Georgia Sedova Str., 4



O. V. Buyuklinskaya
Northern State Medical University of the Ministry of Health Care of Russia; Saint-Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation

Dr. Sci. (Med.), Assoc. Prof.,

163069, Arkhangelsk, Troitskiy Avenue, 51

197376, Saint Petersburg, Professora Popova Str., 14, let. A



O. V. Horeva
Northern State Medical University of the Ministry of Health Care of Russia
Russian Federation

Cand. Sci. (Med.), Assoc. Prof.,

163069, Arkhangelsk, Troitskiy Avenue, 51



References

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2. Milovanova L.N. Tekhnologiya izgotovleniya lekarstvennykh form [Manufacturing technology of drug forms]. Rostov-on-Don: Medicina Publ., 2017:448. (In Russian).

3. Pertsev I.M., Zupants I.A. Farmatsevticheskie i mediko-biologicheskie aspekty primeneniya lekarstvennykh sredstv [Pharmaceutical and biomedical aspects of drugs using]. Kharkov: UkrPhA Publ., 2013:461. (In Russian).

4. Heinrich L.A., Pajaziti B., Roziev R. Drug delivery system of a radio-protective includion Complex. Advanced Materials Research, 2014;872:231–236.


Review

For citations:


Zayats D.V., Buyuklinskaya O.V., Horeva O.V. In vitro determination of the release rate of selenoxanthene synthetic derivative from its soft dosage form. Journal Biomed. 2021;17(3E):28-31. (In Russ.) https://doi.org/10.33647/2713-0428-17-3E-28-31

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ISSN 2074-5982 (Print)
ISSN 2713-0428 (Online)