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Edative activity of a new allylmorpholine derivative in the novel tank diving test in zebrafish Danio rerio

https://doi.org/10.33647/2713-0428-17-3E-161-164

Abstract

A new chromone-containing allylmorpholine derivative, (E)-4-[1-(8-bromo-6-methyl-4-oxo-4H-chromen3-yl)-4-methylpent-1-en-3-yl]morpholin-4-ium chloride, was screened for behavioral effects in zebrafish Danio rerio using the novel tank diving test. Based on the observed alterations in behavior, the compound was confirmed to exert a sedative effect in zebrafish. 

About the Authors

V. A. Prikhodko
St. Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Сare of Russia
Russian Federation

197376, St. Petersburg, Professora Popova Str., 14, let. A



Yu. I. Sysoev
St. Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Сare of Russia; St. Petersburg State University
Russian Federation

Cand. Sci. (Biol.), 197376, St. Petersburg, Professora Popova Str., 14, let. A;

199034, St. Petersburg, Universitetskaya Embankment, 7–9



References

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For citations:


Prikhodko V.A., Sysoev Yu.I. Edative activity of a new allylmorpholine derivative in the novel tank diving test in zebrafish Danio rerio. Journal Biomed. 2021;17(3E):161-164. (In Russ.) https://doi.org/10.33647/2713-0428-17-3E-161-164

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ISSN 2074-5982 (Print)
ISSN 2713-0428 (Online)