Impact of Adaptogens of Animal Origin on Microcirculation in Rats

Abstract

Velvet antler products are adaptogens of animal origin, capable of increasing the physical and mental capacity of the body. It is known that the velvet antler products based the maral blood and a histolysate obtained from the genitals of males exhibit a more pronounced revitalizing effect. Experiments were conducted on 40 mature white male Wistar rats weighing 230±20 g, divided into 3 groups: intact group (n=20); control group (n=10); experimental group (n=10). The experimental group received a concentrate Pantohematogen (Lubyan’gem) at a dose of 2 ml per 100 g of body weight for 30 days; the control group – an aqueous solution of concentrate additives; the intact animals – water in the same volume. On the 31st day of the experiment, the microcirculation indicators of all animals were studied by laser doppler flowmetry. In comparison with intact animals, the rats of the experimental group receiving the concentrate for 30 days showed an increase in the blood flow modulation by 108% (p=0.006), in the amplitude of endothelial fluctuations by 71% (p=0.006), and in the amplitude of vasomotor waves by 45% (p=0.024). This indicates an intensification of the “active” mechanisms of microcirculation regulation.