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Evaluation of the Effect of Phyto-Adaptogens on the Performance Capability of Outbred Female Mice

https://doi.org/10.33647/2074-5982-18-3-99-103

Abstract

The effect of Eleutherococcus senticosus, Rhaponticum carthamoides and Schisandra chinensis extracts in doses of 10, 25, 50 and 75 mg/kg were studied. The actoprotective activity the studied adaptogens was assessed on outbred female mice in a forced swim test with a load of 10% of the animal's body weight. Dry extracts of Eleutherococcus senticosus (50 mg/kg), Rhaponticum carthamoides (10 mg/kg) and Schisandra chinensis (25 mg/kg) were found to exhibit the most pronounced actoprotective activity.

About the Authors

Yu. S. Alekseeva
Saint-Petersburg State Chemical and Pharmaceutical University
Russian Federation

Yuliya S. Alekseeva.

197376, St. Petersburg, Professora Popova Str., 14, lit. A.



Yu. N. Meshcheryakova
Saint-Petersburg State Chemical and Pharmaceutical University
Russian Federation

Yuliya N. Meshcheryakova.

197376, St. Petersburg, Professora Popova Str., 14, lit. A.



Ya. V. Shmakova
Saint-Petersburg State Chemical and Pharmaceutical University
Russian Federation

Yana V. Shmakova.

197376, St. Petersburg, Professora Popova Str., 14, lit. A.



V. Ts. Bolotova
Saint-Petersburg State Chemical and Pharmaceutical University
Russian Federation

Vera Ts. Bolotova - Cand. Sci. (Pharm.), Assoc. Prof., Saint-Petersburg State Chemical and Pharmaceutical University.

197376, St. Petersburg, Professora Popova Str., 14, lit. A.



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Review

For citations:


Alekseeva Yu.S., Meshcheryakova Yu.N., Shmakova Ya.V., Bolotova V.Ts. Evaluation of the Effect of Phyto-Adaptogens on the Performance Capability of Outbred Female Mice. Journal Biomed. 2022;18(3):99-103. (In Russ.) https://doi.org/10.33647/2074-5982-18-3-99-103

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ISSN 2074-5982 (Print)
ISSN 2713-0428 (Online)