Response of Mouse Ovaries to Stimulation witch ihe FSH-SU-PER Drug
https://doi.org/10.33647/2713-0428-19-3E-36-42
Abstract
Hormonal preparation of female egg donors is one of the first stages in obtaining genetically modified animals by microinjected zygote transplantation. A large number of embryos synchronized in development can be obtained by a superovulation procedure based on treating female animals with gonadotropins. As a rule, drugs from different manufacturers differ markedly in terms of their efficacy. In the context of sanctions imposed on the Russian Federation, attention should be paid to domestic hormonal drugs, thus substantiating their objective assessment. It was shown that different batches of the FSH-SUPER drug, used mainly for hormonal treatment of farm animals, differed in stimulating effect on superovulation in female mice. At the same time, the efficacy of this drug surpassed that of Follimag (Mosagrogen, Russia).
About the Authors
O. B. Zhukova
All-Russian Research Institute of Physiology, Biochemistry and Nutrition of Animals — Branch of the Federal Science Center for Animal Husbandry — the All-Russian Institute of Animal Husbandry named after Academician L.K. Ernst
Russian Federation
Russian Federation
Olga B. Zhukova
E. M. Koloskova
All-Russian Research Institute of Physiology, Biochemistry and Nutrition of Animals — Branch of the Federal Science Center for Animal Husbandry — the All-Russian Institute of Animal Husbandry named after Academician L.K. Ernst
Russian Federation
Russian Federation
Elena M. Koloskova - Cand. Sci. (Biol.), All-Russian Research Institute of Physiology.
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Review
For citations:
Zhukova O.B., Koloskova E.M. Response of Mouse Ovaries to Stimulation witch ihe FSH-SU-PER Drug. Journal Biomed. 2023;19(3E):36-42. (In Russ.) https://doi.org/10.33647/2713-0428-19-3E-36-42
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