Influence of Dioscorea Extracts on Physical Load Tolerance in the Setting of Hypoxic and Temperature Factors
https://doi.org/10.33647/2713-0428-19-3E-99-103
Abstract
A comparative evaluation of the effectiveness of dry alcoholic extracts of Dioscorea from pharmacopoeial raw materials and cell cultures was carried out on a model of combined exposure to hypoxic and temperature factors and swimming of laboratory animals (mice) with a load of 5% of body weight. Dioscorea preparations had a pronounced thermoprotective effect and increased physical performance; however, the aftereffect was confirmed only for the cell culture extract.
Supporting agencies: the work was supported by the Russian Science Foundation grant No. 19-14-00387 “Development of biotechnological approaches to obtaining innovative drugs based on higher plant cell cultures for the prevention and treatment of disorders of fat and carbohydrate metabolism”.
About the Authors
A. S. Ivkina
St. Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Arina S. Ivkina
197376, St. Petersburg, Professora Popova Str., 14, Lit. A
D. Yu. Ivkin
St. Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Dmitry Yu. Ivkin - Cand. Sci. (Biol.), Assoc. Prof.
197376, St. Petersburg, Professora Popova Str., 14, Lit. A
E. B. Shustov
St. Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Evgeny B. Shustov - Dr. Sci. (Med.), Prof.
197376, St. Petersburg, Professora Popova Str., 14, Lit. A
M. N. Povydysh
St. Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Maria N. Povydysh - Dr. Sci. (Biol.), Prof.
197376, St. Petersburg, Professora Popova Str., 14, Lit. A
References
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Review
For citations:
Ivkina A.S., Ivkin D.Yu., Shustov E.B., Povydysh M.N. Influence of Dioscorea Extracts on Physical Load Tolerance in the Setting of Hypoxic and Temperature Factors. Journal Biomed. 2023;19(3E):99-103. (In Russ.) https://doi.org/10.33647/2713-0428-19-3E-99-103
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