Screening of Cholinoreceptor Agonists in Experimental Model on Daphnia magna Straus
https://doi.org/10.33647/2074-5982-20-3-58-60
Abstract
The acute toxicity and the ability of cholinoreceptor agonists to induce atypical motor hyperactivity in zoohydrobionts Daphnia magna Straus, equivalent to a significant seizure state in warm-blooded animals, were evaluated. Determination of this test function may be useful in screening assessment of pharmacological activity of cholinergic substances.
About the Author
A. A. Bondarenko
Golikov Research Clinical Center of Toxicology of the Federal Medical and Biological Agency of Russia; Institute of Experimental Medicine
Russian Federation
Russian Federation
Anastasiya A. Bondarenko
192019, Saint Petersburg, Bekhtereva Str., 1
197376, Saint Petersburg, Akademika Pavlova Str., 12
References
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Review
For citations:
Bondarenko A.A. Screening of Cholinoreceptor Agonists in Experimental Model on Daphnia magna Straus. Journal Biomed. 2024;20(3):58-60. (In Russ.) https://doi.org/10.33647/2074-5982-20-3-58-60
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