Effectiveness and Safety of Modern Hemostatics Based on Chitosan and Kaolin

Abstract

There exist numerous local hemostatic agents; however, their disadvantages, such as a short shelf life, high cost, lack of antiseptic properties, a single mechanism of action, residual toxicity, etc., require the development of new materials capable of meeting as many requirements for an “ideal” hemostatic as possible. Meanwhile, regardless of the mechanism of injury, the implementation of hemostasis is of crucial importance for eliminating the consequences of acute bleeding until the provision of the necessary medical care. This article discusses the safety and effectiveness of some of the most promising local hemostatics, in particular, those created from chitosan and kaolin.