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Assessment of the Wound-Healing Effect of Hydrogels on an Experimental Burn Model in Rodents

https://doi.org/10.33647/2713-0428-20-3E-211-215

Abstract

The article presents the results of a research study into the effectiveness of hydrogels containing calcium complexes and/or ionomers based on copper (II) complexes on the healing rate of a wound surface formed by a thermal burn.

About the Authors

E. D. Semivelichenko
Saint Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation

Evgeniy D. Semivelichenko 

197376, Saint Petersburg, Professora Popova Str., 14, lit. A



A. S. Romanovsky
Saint Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation

Anton S. Romanovsky 

197376, Saint Petersburg, Professora Popova Str., 14, lit. A



A. V. Eremin
Branch of Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Center “Kurchatov Institute” — Institute of Macromolecular Compounds
Russian Federation

Aleksey V. Eremin, Cand. Sci. (Chem.), Assoc. Prof. 

199004, Saint Petersburg, Vasilievsky Island, Bolshoy Ave., 31



S. M. Napalkova
Saint Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation

Svetlana M. Napalkova, Dr. Sci. (Biol.), Prof. 

197376, Saint Petersburg, Professora Popova Str., 14, lit. A



O. V. Buyuklinskaya
Saint Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation

Olga V. Buyuklinskaya, Dr. Sci. (Med.), Prof. 

197376, Saint Petersburg, Professora Popova Str., 14, lit. A



References

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2. Semivelichenko E.D., Ermolaeva A.A., Ponomarenko V.V., Novoselov A.V., Plisko G.A., Ivkin D.Yu., Antonov V.G., Karev V.E., Titovich I.A., Eremin A.V. Issledovanie effektivnosti deystviya preparatov na osnove molekulyarnykh kompleksov adenozin-polimer na modeli termicheskogo ozhoga [Study of the effectiveness of drugs based on molecular complexes of adenosine-polymer on the model of thermal burn]. Razrabotka i registratsiya lekarstvennykh sredstv [Drug Development & Registration]. 2022;11(3):209–219. (In Russian). DOI: 10.33380/2305-2066-2022-11-3-209-219

3. ShabuninA.S., Zinoviev E.V., Vissarionov S.V., Asadulaev M.S., Makarov A.Yu., Fedyuk A.M., Rybinskikh T.S., Pershina P.A., Kostyakov D.V., Semiglazov A.V., Pyatakova S.N. Otsenka effektivnosti lecheniya ozhogov 3 stepeni peptidom hldf6 i nanochastitsami serebra v gele carbopol 2020 v eksperimente in vivo [Evaluation of the efficacy of treatment of 3rd degree burns with hldf6 peptide and silver nanoparticles in carbopol 2020 gel in vivo experiment]. Rossiyskie biomeditsinskie issledovaniya [Russian Biomedical Research]. 2023;8(3):4–10. (In Russian). DOI: 10.56871/RBR.2023.37.44.001

4. Ho T.C., Chang C.C., Chan H.P., Chung T.W., ShuC.W., Chuang K.P., Duh T.H., Yang M.H., Tyan Y.C. Hydrogels: Properties and applications in biomedicine. Molecules. 2022;27(9):2902. DOI: 10.3390/molecules27092902

5. Markiewicz-Gospodarek A., Kozioł M., Tobiasz M., Baj J., Radzikowska-Büchner E., Przekora A. Burn wound healing: Clinical complications, medical care, treatment, and dressing types: The current state of knowledge for clinical practice. Int. J. Environ. Res. Public Health. 2022;19(3):1338. DOI: 10.3390/ijerph19031338


Review

For citations:


Semivelichenko E.D., Romanovsky A.S., Eremin A.V., Napalkova S.M., Buyuklinskaya O.V. Assessment of the Wound-Healing Effect of Hydrogels on an Experimental Burn Model in Rodents. Journal Biomed. 2024;20(3E):211-215. (In Russ.) https://doi.org/10.33647/2713-0428-20-3E-211-215

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ISSN 2074-5982 (Print)
ISSN 2713-0428 (Online)