Adapter for Analysis of Animal Brain γ-Oscillation for Screening the Effects of Neurotropic Drugs and Cognitive Functions
https://doi.org/10.33647/2074-5982-21-3-30-34
Abstract
High-frequency components of brain activity (γ-rhythms, over 30 Hz) are the key markers of cognitive processes. Their study is relevant for diagnostics, treatment, and prevention of neurodegenerative diseases and obsessive-compulsive disorders, including schizophrenia, epilepsy, Alzheimer's disease, etc., as well as for the development and screening of drug effects. The lack of serially-produced equipment with the technical parameters required for research and ready-made invasive systems with the capacity to analyze the high-frequency range of brain activity, as well as the current geopolitical situation, prompted us to create a domestic biopotential amplifier.
Keywords
brain electrograms,
gamma rhythms,
normalization,
cognitive functions,
neurotropic agents,
pharmaco-EEG analysis
Supporting agencies: the work was carried out within the framework of the state assignment of the Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia on the topic “Establishing the role of the gamma range of normalized electrograms of the animal brain in the intracentral mechanisms of nootropic effects” (code: “Nootrop-2024”)
About the Authors
S. Yu. Kharitonov
Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Sergey Yu. Kharitonov
143442, Moscow Region, Krasnogorsk District, Svetlye Gory Village, 1
Yu. V. Fokin
Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Yuriy V. Fokin - Cand. Sci. (Biol.).
143442, Moscow Region, Krasnogorsk District, Svetlye Gory Village, 1
N. N. Karkischenko
Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Nikolay N. Karkischenko - Academician of the Russian Academy of Rocket and Artillery Sciences, Corresponding Member of the Russian Academy of Sciences, Dr. Sci. (Med.), Prof.
143442, Moscow Region, Krasnogorsk District, Svetlye Gory Village, 1
References
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Review
For citations:
Kharitonov S.Yu., Fokin Yu.V., Karkischenko N.N. Adapter for Analysis of Animal Brain γ-Oscillation for Screening the Effects of Neurotropic Drugs and Cognitive Functions. Journal Biomed. 2025;21(3):30-34. (In Russ.) https://doi.org/10.33647/2074-5982-21-3-30-34
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