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Biochemical Markers of Multiple Organ Failure (Organ Dysfunction) in Experimental Modeling of Internal Intestinal Fistulas

https://doi.org/10.33647/2074-5982-21-3-68-72

Abstract

In experiments on 20 rats, biochemical markers of organ dysfunction were assessed 6 and 24 h after modeling internal intestinal fistulas. It was found that biochemical markers of organ dysfunction allow early detection of impaired protein-synthetic function of the liver, development of cytolysis and cholestasis syndrome, and impaired renal function after modeling internal intestinal fistulas.

About the Authors

N. S. Tropskaya
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department; Moscow Aviation Institute (National Research University)
Russian Federation

Nataliya S. Tropskaya - Dr. Sci. (Biol.)

129090, Moscow, Bolshaya Sukharevskaya Sq., 3; 125993, Moscow, Volokolamskoe Highway, 4



E. V. Klychnikova
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department
Russian Federation

Elena V. Klychnikova - Cand. Sci. (Med.).

125993, Moscow, Volokolamskoe Highway, 4



E. A. Kislykova
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department
Russian Federation

Ekaterina A. Kislykova - Cand. Sci. (Biol.).

125993, Moscow, Volokolamskoe Highway, 4



I. G. Vilkova
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department
Russian Federation

Irina G. Vilkova

125993, Moscow, Volokolamskoe Highway, 4



O. S. Kislitsyna
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department
Russian Federation

Oksana S. Kislitsyna

125993, Moscow, Volokolamskoe Highway, 4



Yu. V. Gurman
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department
Russian Federation

Yulia V. Gurman

125993, Moscow, Volokolamskoe Highway, 4



O. V. Razbitskaya
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department
Russian Federation

Olga V. Razbitskaya

125993, Moscow, Volokolamskoe Highway, 4



A. Yu. Anurov
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department
Russian Federation

Artem Yu. Anurov

125993, Moscow, Volokolamskoe Highway, 4



References

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Review

For citations:


Tropskaya N.S., Klychnikova E.V., Kislykova E.A., Vilkova I.G., Kislitsyna O.S., Gurman Yu.V., Razbitskaya O.V., Anurov A.Yu. Biochemical Markers of Multiple Organ Failure (Organ Dysfunction) in Experimental Modeling of Internal Intestinal Fistulas. Journal Biomed. 2025;21(3):68-72. (In Russ.) https://doi.org/10.33647/2074-5982-21-3-68-72

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ISSN 2074-5982 (Print)
ISSN 2713-0428 (Online)