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Influence of Body Temperature during Acute Blood Loss on the Locomotor and Exploratory Activity of Animals in the Posthemorrhagic Period

https://doi.org/10.33647/2074-5982-21-3-73-77

Abstract

In experiments on 55 rats, the effect of body temperature during acute blood loss on the locomotor and exploratory activity of animals on days 3 and 7 of the posthemorrhagic period was assessed. A decrease in exploratory and locomotor activity in animals that had undergone acute blood loss under normothermia was detected. Acute massive blood loss performed under hypothermia does not affect exploratory and locomotor activity, which may indicate neuroprotective mechanisms of natural cooling.

About the Authors

N. S. Tropskaya
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department; Moscow Aviation Institute (National Research University)
Russian Federation

Nataliya S. Tropskaya - Dr. Sci. (Biol.).

129090, Moscow, Bolshaya Sukharevskaya Sq., 3; 125993, Moscow, Volokolamskoe Highway, 4



R. A. Cherpakov
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology
Russian Federation

Rostislav A. Cherpakov - Cand. Sci. (Med.).

129090, Moscow, Bolshaya Sukharevskaya Sq., 3; 107031, Moscow, Petrovka Str., 25/2



Yu. V. Gurman
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department
Russian Federation

Yulia V. Gurman

129090, Moscow, Bolshaya Sukharevskaya Sq., 3



E. A. Kislykova
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department
Russian Federation

Ekaterina A. Kislykova - Cand. Sci. (Biol.)

129090, Moscow, Bolshaya Sukharevskaya Sq., 3



O. S. Kislitsyna
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department
Russian Federation

Oksana S. Kislitsyna

129090, Moscow, Bolshaya Sukharevskaya Sq., 3



A. K. Shabanov
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology
Russian Federation

Aslan K. Shabanov - Dr. Sci. (Med.).

129090, Moscow, Bolshaya Sukharevskaya Sq., 3; 107031, Moscow, Petrovka Str., 25/2



S. S. Petrikov
N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Health Care Department
Russian Federation

Sergey S. Petrikov - Acad. of the Russian Academy of Sciences.

129090, Moscow, Bolshaya Sukharevskaya Sq., 3



References

1. Andresen M., Gazmuri J.T., Marín A., Regueira T., Rovegno M. Therapeutic hypothermia for acute brain injuries. Scand. J. Trauma Resusc. Emerg. Med. 2015;23:42. DOI: 10.1186/s13049-015-0121-3.

2. Siegel J.H. The effect of associated injuries, blood loss, and oxygen debt on death and disability in blunt traumatic brain injury: the need for early physiologic predictors of severity. J. Neurotrauma. 1995;12(4):579–590. DOI: 10.1089/neu.1995.12.579.

3. van Veelen M.J., Brodmann Maeder M. Hypothermia in Trauma. Int. J. Environ Res. Public Health. 2021;18(16):8719. DOI: 10.3390/ijerph18168719.


Review

For citations:


Tropskaya N.S., Cherpakov R.A., Gurman Yu.V., Kislykova E.A., Kislitsyna O.S., Shabanov A.K., Petrikov S.S. Influence of Body Temperature during Acute Blood Loss on the Locomotor and Exploratory Activity of Animals in the Posthemorrhagic Period. Journal Biomed. 2025;21(3):73-77. (In Russ.) https://doi.org/10.33647/2074-5982-21-3-73-77

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ISSN 2074-5982 (Print)
ISSN 2713-0428 (Online)