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Repetitive Nerve Stimulation for Functional Assessment of Neuromuscular Transmission in Experimental Studies

https://doi.org/10.33647/2074-5982-21-3-78-81

Abstract

This article presents a comparative description of typical electromyographic patterns of neuromuscular transmission disturbances due to effects of various cholinergic agents. The results obtained can be used when modeling pathologies of the peripheral nervous system and conducting preclinical studies in the field of neuropharmacology and neurotoxicology.

About the Authors

M. I. Tyunin
State Scientific Research Testing Institute of Military Medicine of the Ministry of Defence of Russia
Russian Federation

Mikhail A. Tyunin - Cand. Sci. (Med.)

195043, Saint Petersburg, Lesoparkovaya Str., 4



V. A. Macejchik
Departament of Science and Innovative Development of the Ministry of Health Сare of Russia
Russian Federation

Vladimir A. Macejchik

127994, Moscow, Rakhmanovskyj Lane, 3



N. S. Ilinskiy
State Scientific Research Testing Institute of Military Medicine of the Ministry of Defence of Russia
Russian Federation

Nikita S. Ilinskiy - Cand. Sci. (Med.).

195043, Saint Petersburg, Lesoparkovaya Str., 4



I. V. Starshova
State Scientific Research Testing Institute of Military Medicine of the Ministry of Defence of Russia
Russian Federation

Irina V. Starshova

195043, Saint Petersburg, Lesoparkovaya Str., 4



E. Yu. Izhorskaya
State Scientific Research Testing Institute of Military Medicine of the Ministry of Defence of Russia
Russian Federation

Elizaveta Yu. Izhorskaya

195043, Saint Petersburg, Lesoparkovaya Str., 4



References

1. Ilinskiy N.S., Tyunin M.A., Matrosova M.O. Metodicheskie podhody k ocenke paraliticheskogo sindroma toksicheskogo genesa v eksperimentah na gryzunah [Methodological approaches to the assessment of paralytic syndrome of toxic genesis in experiments of rodents]. Lab. jyv. dlya nauchn. issled. [Lab. anim. for sci.]. 2021;(3):70–74. (In Russian).

2. Fundamentals of Toxicology. Essential Concepts and Applications. Ed. By P.K. Gupta. London: Academic Press, 2016:221–244.

3. Harris J.B., Blain P.G. Neurotoxicology: what the neurologist needs to know. J. of Neurol., Neurosurg. & Psych. 2004;75:iii29–iii34. DOI: 10/1136/jnnp.2004.046318.


Review

For citations:


Tyunin M.I., Macejchik V.A., Ilinskiy N.S., Starshova I.V., Izhorskaya E.Yu. Repetitive Nerve Stimulation for Functional Assessment of Neuromuscular Transmission in Experimental Studies. Journal Biomed. 2025;21(3):78-81. (In Russ.) https://doi.org/10.33647/2074-5982-21-3-78-81

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ISSN 2074-5982 (Print)
ISSN 2713-0428 (Online)