Immunomodulatory Properties of Essential Oils from the Fruits of Coriandrum sativum and Foeniculum vulgare mill
https://doi.org/10.33647/2074-5982-21-3-92-96
Abstract
Secondary metabolites of essential oil crops are capable of exhibiting antibacterial, anti-inflammatory, and immunostimulatory properties in human and animal organisms. In this study, we investigate the immunomodulatory effect of coriander and fennel essential oils using swine models as those most similar to the physiological state of humans. The immune status was assessed by determining the expression of IL-6 and IL-8 genes in swine blood leucocytes. The results established a significant decrease in the expression of cytokines in the experimental groups compared with the control group: IL-6 and IL-8 by 4.69 and 19.31 times in group 1, and by 9.15 and 3.54 times in group 2. The essential oils under investigation were established to demonstrate immunomodulatory effects, allowing animals and humans to respond more plasticity to external factors of various genesis.
About the Authors
Yu. A. Volchenkov
All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition — Branch of the Federal Scientific Center of Animal Husbandry — The All-Russian Institute of Animal Husbandry named after Academician L.K. Ernst
Russian Federation
Russian Federation
Yuri A. Volchenkov
249013, Kaluga Region, Borovsk, Institut Village
K. S. Ostrenko
All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition — Branch of the Federal Scientific Center of Animal Husbandry — The All-Russian Institute of Animal Husbandry named after Academician L.K. Ernst
Russian Federation
Russian Federation
Konstantin S. Ostrenko - Dr. Sci. (Biol.).
249013, Kaluga Region, Borovsk, Institut Village
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Review
For citations:
Volchenkov Yu.A., Ostrenko K.S. Immunomodulatory Properties of Essential Oils from the Fruits of Coriandrum sativum and Foeniculum vulgare mill. Journal Biomed. 2025;21(3):92-96. (In Russ.) https://doi.org/10.33647/2074-5982-21-3-92-96
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