Development of New Composite Materials for Facial Skeleton Reconstruction After Oncologic Surgery
https://doi.org/10.33647/2074-5982-21-4-73-76
Abstract
A set of preclinical trials was conducted to study the biomedical properties of personalized model implants based on aluminum oxide in the reconstruction of facial skeletal defects and to substantiate the advantages of their use. The study involved cell cultures and laboratory animals, including at least 30 small-sized laboratory animals (mice or rats) and at least 20 medium-sized laboratory animals (rabbits). The advantages of model implants based on aluminum oxide and titanium aluminum for facial skeletal reconstruction are demonstrated. On their basis, the relevance of integrating the discussed approach into conventional surgical treatment for the majority of patients requiring reconstruction is substantiated.
About the Authors
A. A. Nebezhev
I.M. Sechenov First Moscow State Medical University of the Ministry of Health Care of Russia (Sechenov University)
Russian Federation
Russian Federation
Alim A. Nebezhev
119048, Moscow, Trubetskaya Str., 8, Build. 2I. V. Reshetov
I.M. Sechenov First Moscow State Medical University of the Ministry of Health Care of Russia (Sechenov University)
Russian Federation
Russian Federation
Igor V. Reshetov, Dr. Sci. (Med.), Prof., Acad. of the Russian Academy of Sciences
119048, Moscow, Trubetskaya Str., 8, Build. 2References
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For citations:
Nebezhev A.A., Reshetov I.V. Development of New Composite Materials for Facial Skeleton Reconstruction After Oncologic Surgery. Journal Biomed. 2025;21(4):73-76. (In Russ.) https://doi.org/10.33647/2074-5982-21-4-73-76
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