Experience of Carbon Ion Radiotherapy Using a U-70 Accelerator Complex
https://doi.org/10.33647/2074-5982-21-4-101-104
Abstract
Radiobiological effects of the therapeutic beam of carbon ions were studied using a U-70 acceleration complex in mice subjected to total irradiation. Following 30-day survival, a micronucleus test was conducted. The values of relative biological effectiveness (RBE) were determined depending on the dose, linear energy transfer (LET) of carbon ions, and the method of damage registration.
Keywords
carbon ion,
X-rays,
relative biological effectiveness,
linear energy transfer,
mice,
micronuclei,
30-day survival rate
Supporting agencies: the work was carried out within fundamental scientific research on the topic of State assignment No. 075-00223-25-00.
About the Authors
T. A. Belyakova
Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences; Institute for High Energy Physics named after A.A. Logunov of the National Research Centre “Kurchatov Institute”
Russian Federation
Russian Federation
Tatiana A. Belyakova
142290, Moscow Region, Pushchino, Institutskaya Str., 3
142281, Moscow Region, Protvino, Science Sq., 1
O. M. Rozanova
Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences
Russian Federation
Russian Federation
Olga M. Rozanova
142290, Moscow Region, Pushchino, Institutskaya Str., 3
E. N. Smirnova
Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences
Russian Federation
Russian Federation
Elena N. Smirnova
142290, Moscow Region, Pushchino, Institutskaya Str., 3
N. S. Strelnikova
Branch “Physical Tech- nical Center”, P.N. Lebedev Physical Institute of the Russian Academy of Sciences
Russian Federation
Russian Federation
Nataliia S. Strelnikova
142281, Moscow Region, Protvino, Mira Str., 1Н
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Review
For citations:
Belyakova T.A., Rozanova O.M., Smirnova E.N., Strelnikova N.S. Experience of Carbon Ion Radiotherapy Using a U-70 Accelerator Complex. Journal Biomed. 2025;21(4):101-104. (In Russ.) https://doi.org/10.33647/2074-5982-21-4-101-104
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