Efficacy of Lyophilisate of Sea Urchin Strongylocentrotus droebachiensis under the Influence of Adverse Factors
https://doi.org/10.33647/2074-5982-21-4-129-133
Abstract
The efficacy of Strongylocentrotus droebachiensis gonad lyophilisate in combined poisoning with carbendazim and X-ray irradiation was assessed in rat biomodels. Two-week intragastric administration of the lyo- philisate was shown to partially compensate for the changes caused by adverse factors, as the same time as exhibiting antioxidant, hemopoetic, and anabolic aciton.
Keywords
Supporting agencies: this work was performed in the framework of State task of the Federal Medical Biological Agency No. 388-00113-21-00 (code: 64.003.21.800).
About the Authors
M. V. Melnikova
Golikov Research Clinical Center of Toxicology of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Margarita V. Melnikova
192019, Saint Petersburg, Bekhtereva Str., 1
E. B. Shustov
Golikov Research Clinical Center of Toxicology of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Evgeny B. Shustov, Dr. Sci. (Med.), Prof.
192019, Saint Petersburg, Bekhtereva Str., 1
E. G. Batotsyrenova
Golikov Research Clinical Center of Toxicology of the Federal Medical and Biological Agency of Russia; St. Petersburg State Pediatric Medical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Ekaterina G. Batotsyrenova, Dr. Sci. (Biol.), Assoc. Prof.,
192019, Saint Petersburg, Bekhtereva Str., 1
194100, Saint-Petersburg, Litovskaya Str., 2
L. G. Kubarskaya
Golikov Research Clinical Center of Toxicology of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Larisa G. Kubarskaya, Cand. Sci. (Biol.)
192019, Saint Petersburg, Bekhtereva Str., 1
A. Bondarenko
Golikov Research Clinical Center of Toxicology of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Anastasiya A. Bondarenko
192019, Saint Petersburg, Bekhtereva Str., 1
А. V. Belskaya
Golikov Research Clinical Center of Toxicology of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Alisa V. Belskaya
192019, Saint Petersburg, Bekhtereva Str., 1
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Review
For citations:
Melnikova M.V., Shustov E.B., Batotsyrenova E.G., Kubarskaya L.G., Bondarenko A., Belskaya А.V. Efficacy of Lyophilisate of Sea Urchin Strongylocentrotus droebachiensis under the Influence of Adverse Factors. Journal Biomed. 2025;21(4):129-133. (In Russ.) https://doi.org/10.33647/2074-5982-21-4-129-133
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