Pharmakokinetics and clinical efficacy of the lipid-lowering drug Atorvastatin
Abstract
The pharmacokinetics of lipid-lowering drug of the statin – Аtorvastatin by HPLC In 18 healthy humans are examined. In 30 patients with hyperlipidemia studied the clinical efficacy of Atorvastatin. The treatment marked by a pronounced gipolipidnemic effect with a significant decrease in atherogenic lipides profile. A slight antiplatelet effect of this drug also noted.
About the Authors
A. S. Sivkov
Первый МГМУ им. И.М. Сеченова, Минздравсоцразвития РФ
Russian Federation
Russian Federation
S. K. Sivkova
Первый МГМУ им. И.М. Сеченова, Минздравсоцразвития РФ
Russian Federation
Russian Federation
V. G. Kukes
Первый МГМУ им. И.М. Сеченова, Минздравсоцразвития РФ
Russian Federation
Russian Federation
G. V. Ramenskaya
Первый МГМУ им. И.М. Сеченова, Минздравсоцразвития РФ
Russian Federation
Russian Federation
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Review
For citations:
Sivkov A.S., Sivkova S.K., Kukes V.G., Ramenskaya G.V. Pharmakokinetics and clinical efficacy of the lipid-lowering drug Atorvastatin. Journal Biomed. 2012;1(3):79-84. (In Russ.)
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