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Discriminant Analysis of the Coordinated Work Indicators of the Heart and Blood Vessels in Health and Disease

https://doi.org/10.33647/2074-5982-17-2-8-21

Abstract

A discriminant method was proposed for modeling and quantifying the consistency of regulatory mechanisms in the cardiovascular system (CVS) of apparently healthy volunteers and those suffering from circulatory disorders associated with cervical spine osteochondrosis (OCS) and somatoform autonomic dysfunction (SAD). The congruence of the parameters of ECG intervalometry (DCI) and pulse wave duration (PWD) according to the volunteers’ photoplethysmograms (PPG) was established by calculating the disparity measure and deviations from the mean values using the coeffi cients of displacement, slope of the approximating straight line, as well as by comparing the reliability and correlation of the trend model with the initial data. We discovered gross violations of congruence in the work of efferent and afferent regulatory CVS mechanisms, mismatch and decrease in comparison with the norm of DCI and PWD, a signifi cant decrease in their approximation in the SAD volunteers. In volunteers with OCS, deviations in DCI and PWD from their mean values are much lower than in those with SAD, being inferior compared to healthy volunteers. Similar to SAD, these patients are inferior to healthy volunteers in terms of the disparity measure. 

About the Authors

N. N. Karkischenko
Scientifi c Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia
Russian Federation

Nikolay N. Karkischenko, Academician of the Russian Academy of Rocket and Artillery Sciences, Corresponding Member of the Russian Academy of Sciences, Dr. Sci. (Med.), Prof.

143442, Moscow region, Krasnogorsk District, Svetlye Gory Village, 1



D. B. Chaivanov
National Research Center “Kurchatov Institute”
Russian Federation

Dmitry B. Chaivanov, Cand. Sci. (Phis.-Math.)

123182,  Moscow, Akademika Kurchatova Square, 1



Y. A. Chudina
National Research Center “Kurchatov Institute”
Russian Federation

Yulia A. Chudina

123182,  Moscow, Akademika Kurchatova Square, 1



A. A. Nikolaev
National Research Center “Kurchatov Institute”
Russian Federation

Andrey А. Nikolaev

123182,  Moscow, Akademika Kurchatova Square, 1



A. A. Vartanov
National Research Center “Kurchatov Institute”
Russian Federation

Alexander A. Vartanov

123182,  Moscow, Akademika Kurchatova Square, 1



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Review

For citations:


Karkischenko N.N., Chaivanov D.B., Chudina Y.A., Nikolaev A.A., Vartanov A.A. Discriminant Analysis of the Coordinated Work Indicators of the Heart and Blood Vessels in Health and Disease. Journal Biomed. 2021;17(2):8-21. (In Russ.) https://doi.org/10.33647/2074-5982-17-2-8-21

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ISSN 2074-5982 (Print)
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