A Model of a Novel Coronavirus Infection in Golden Syrian Hamsters: Major Pathological Changes
https://doi.org/10.33647/2074-5982-17-3-90-94
Abstract
The paper presents data on the dynamics of body weight and mass coeffi cient of lungs in golden Syrian hamsters after infection with the SARS CoV-2 virus. It was found that the most pronounced deviations of the studied parameters develop on the 7th day of the disease. The study also demonstrates the main histopathological changes in the lungs during this period of the disease.
About the Authors
S. V. Chepur
State Scientific Research Testing Institute of Military Medicine of the Ministry of Defense of Russia
Russian Federation
Russian Federation
Sergey V. Chepur, Dr. Sci. (Med.)
195043, Russian Federation, Saint Petersburg, Lesoparkovaya Str., 4
V. A. Myasnikov
State Scientific Research Testing Institute of Military Medicine of the Ministry of Defense of Russia
Russian Federation
Russian Federation
Vadim A. Myasnikov, Cand. Sci. (Med.)
195043, Russian Federation, Saint Petersburg, Lesoparkovaya Str., 4
M. A. Tyunin
State Scientific Research Testing Institute of Military Medicine of the Ministry of Defense of Russia
Russian Federation
Russian Federation
Mikhail A. Tyunin, Cand. Sci. (Med.)
195043, Russian Federation, Saint Petersburg, Lesoparkovaya Str., 4
N. S. Ilinskiy
State Scientific Research Testing Institute of Military Medicine of the Ministry of Defense of Russia
Russian Federation
Russian Federation
Nikita S. Ilinskiy
195043, Russian Federation, Saint Petersburg, Lesoparkovaya Str., 4
A. S. Nikishin
State Scientific Research Testing Institute of Military Medicine of the Ministry of Defense of Russia
Russian Federation
Russian Federation
Alexandr S. Nikishin
195043, Russian Federation, Saint Petersburg, Lesoparkovaya Str., 4
A. A. Isaeva
State Scientific Research Testing Institute of Military Medicine of the Ministry of Defense of Russia
Russian Federation
Russian Federation
Anastasiya A. Isaeva
195043, Russian Federation, Saint Petersburg, Lesoparkovaya Str., 4
V. A. Shevchenko
State Scientific Research Testing Institute of Military Medicine of the Ministry of Defense of Russia
Russian Federation
Russian Federation
Valentin A. Shevchenko
195043, Russian Federation, Saint Petersburg, Lesoparkovaya Str., 4
References
1. Imai M. Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development. PNAS. 2020;117(28):16587–16595.
2. Tostanoski L.H. Ad26 vaccine protects against SARSCoV-2 sereve clinical disease in hamsters. Nat. Med. 2020. DOI 10/1038/s41591-020-1070-6.
Review
For citations:
Chepur S.V., Myasnikov V.A., Tyunin M.A., Ilinskiy N.S., Nikishin A.S., Isaeva A.A., Shevchenko V.A. A Model of a Novel Coronavirus Infection in Golden Syrian Hamsters: Major Pathological Changes. Journal Biomed. 2021;17(3):90-94. (In Russ.) https://doi.org/10.33647/2074-5982-17-3-90-94
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