1,3-Diethylbenzimidazolium Triodide in Pharmacotherapy of Chronic Compensated Tonsillopharyngitis
https://doi.org/10.33647/2074-5982-17-3-111-118
Abstract
The article presents the results of a clinical and bacteriological assessment of the pharmacological efficacy of 1,3-diethylbenzimidazolium triiodide in chronic compensated tonsillopharyngitis. As a result of a 10-day course of treatment, an improvement in the clinical status of patients was achieved, as well as a significant positive effect on the composition of the pharyngeal microbiocenosis. In particular, the content of Staphylococcus aureus, β-hemolytic streptococci, Escherichia signifi cantly decreased, and Enterobacteria, non-fermenting bacteria, and Streptococci pneumonia completely disappeared from the microbial focus. However, the conducted 10-day treatment did not lead to the complete disappearance of α-hemolytic and non-hemolytic streptococci from the microbial population. This may be explained by the reparative effect of Stellanin® on the lymphoid formations of the pharynx, contributing to the restoration of colonization resistance.
About the Authors
E. K. Meloyan
Rostov State Medical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Elena K. Meloyan
344022, Russian Federation Rostov-on-Don, Nakhichevanskiy Lane, 29
A. V. Safronenko
Rostov State Medical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Andrey V. Safronenko, Dr. Sci. (Med.), Assoc. Prof.
344022, Russian Federation Rostov-on-Don, Nakhichevanskiy Lane, 29
E. V. Gantsgorn
Rostov State Medical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Elena V. Gantsgorn, Cand. Sci. (Med.), Assoc. Prof.
344022, Russian Federation Rostov-on-Don, Nakhichevanskiy Lane, 29
L. E. Hmara
Rostov State Medical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Lyubov E. Hmara, Cand. Sci. (Med.), Assoc. Prof.
344022, Russian Federation Rostov-on-Don, Nakhichevanskiy Lane, 29
A. O. Golubeva
Rostov State Medical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Anna O. Golubeva
344022, Russian Federation Rostov-on-Don, Nakhichevanskiy Lane, 29
M. A. Jabr
Rostov State Medical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Mohamad A. Jabr
344022, Russian Federation Rostov-on-Don, Nakhichevanskiy Lane, 29
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Review
For citations:
Meloyan E.K., Safronenko A.V., Gantsgorn E.V., Hmara L.E., Golubeva A.O., Jabr M.A. 1,3-Diethylbenzimidazolium Triodide in Pharmacotherapy of Chronic Compensated Tonsillopharyngitis. Journal Biomed. 2021;17(3):111-118. (In Russ.) https://doi.org/10.33647/2074-5982-17-3-111-118
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