Structural and functional properties of thermolable bacteriocin produced by the Limosilactobacillus fermentum IIE MD-150 strain

Abstract

Bacteriocins are bacterial proteins or peptides exhibiting antimicrobial activity and synthesized on ribosomes. For a high molecular weight bacteriocin produced by the Limosilactobacillus fermentum IIE MD-150 strain and having the GRAS status (Generally Recognized as Safe), an amino acid sequence homology with enterolysin A produced by the Enterococus faecalis LMG 2333 strain was found. Lactobacillus fermentum IIE MD-150 can be used in the prevention and complex treatment of infectious diseases caused by antibiotic-resistant strains of Staphylococcus aureus.