Structural and functional properties of thermolable bacteriocin produced by the Limosilactobacillus fermentum IIE MD-150 strain
https://doi.org/10.33647/2713-0428-17-3E-114-117
Abstract
Bacteriocins are bacterial proteins or peptides exhibiting antimicrobial activity and synthesized on ribosomes. For a high molecular weight bacteriocin produced by the Limosilactobacillus fermentum IIE MD-150 strain and having the GRAS status (Generally Recognized as Safe), an amino acid sequence homology with enterolysin A produced by the Enterococus faecalis LMG 2333 strain was found. Lactobacillus fermentum IIE MD-150 can be used in the prevention and complex treatment of infectious diseases caused by antibiotic-resistant strains of Staphylococcus aureus.
About the Authors
A. V. MachulinRussian Federation
Cand. Sci. (Biol.),
142290, Moscow Region, Pushchino, Science Avenue, 3
I. V. Kosarev
Russian Federation
Cand. Sci. (Biol.),
142380, Moscow Region, Chekhov District, Lyubuchany, Nauchnaya Str., 1
T. N. Abashina
Russian Federation
V. M. Abramov
Russian Federation
Cand. Sci. (Biol.),
142380, Moscow Region, Chekhov District, Lyubuchany, Nauchnaya Str., 1
V. N. Uversky
United States
Dr. Sci. (Biol.), Prof.,
33620, Florida, Tampa, 4202 E. Fowler Avenue
A. V. Karlyshev
United Kingdom
Dr. Sci. (Phys.-Math.), Prof.,
KT1 1LQ, London, Surrey, Kingston upon Thames, 53–57 High Str., River House
Review
For citations:
Machulin A.V., Kosarev I.V., Abashina T.N., Abramov V.M., Uversky V.N., Karlyshev A.V. Structural and functional properties of thermolable bacteriocin produced by the Limosilactobacillus fermentum IIE MD-150 strain. Journal Biomed. 2021;17(3E):114-117. (In Russ.) https://doi.org/10.33647/2713-0428-17-3E-114-117