METHODS FOR ESTIMATING NEUROLOGICAL DISTURBANCES IN EXPERIMENTAL CEREBRAL ISCHEMIA
https://doi.org/10.33647/2074-5982-15-2-69-74
Abstract
Investigation of the brain pathology in experimental ischemia requires adequate methods for assessing the neurological deficit that occurs in laboratory animals, including sensory-based and behavioural disorders. In this research, we aimed to compare motor and behavioural disorders in rats with partial and subtotal experimental cerebral ischemia. The rats modelled with cerebral ischemia are found to exhibit a decrease in muscle strength, resistance to hypoxia, motor and emotional activity. The animals with incomplete cerebral ischemia demonstrated more pronounced sensory-based motor and behavioural disorders compared both with those modelled with partial cerebral ischemia and, in particular, with the control group.
About the Authors
E. I. Bon
Grodno State Medical University
Belarus
Belarus
Cand. Sci. (Biol.),
230009, Republic of Belarus, Grodno, Gorkogo str., 80
N. Ye. Maksimovich
Grodno State Medical University
Belarus
Belarus
Dr. Sci. (Med.), Prof.,
230009, Republic of Belarus, Grodno, Gorkogo str., 80
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Review
For citations:
Bon E.I., Maksimovich N.Ye. METHODS FOR ESTIMATING NEUROLOGICAL DISTURBANCES IN EXPERIMENTAL CEREBRAL ISCHEMIA. Journal Biomed. 2019;(2):69-74. https://doi.org/10.33647/2074-5982-15-2-69-74
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