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COVID-19 Convalescents Exhibit Humoral Immunity to SARS-COV-2 Envelope (E) Protein

https://doi.org/10.33647/2074-5982-18-3-32-36

Abstract

In this work, we obtain a producer of the recombinant SARS-CoV-2 E protein and develop a system for its expression and purification in a soluble form. ELISA confirmed its antigenic properties. In COVID-19 convalescents, the level of IgG against the E protein was significantly increased in comparison with the control group of patients.

About the Authors

E. A. Orlova
Scientific Centre for Family Health and Human Reproduction Problems
Russian Federation

Elizaveta A. Orlova.

664003, Irkutsk, Timiryazeva Str., 16.



I. G. Kondratov
Scientific Centre for Family Health and Human Reproduction Problems
Russian Federation

Ilya G. Kondratov - Cand. Sci. (Biol.), Scientific Centre for Family Health and Human Reproduction Problems.

664003, Irkutsk, Timiryazeva Str., 16.



O. B. Ogarkov
Scientific Centre for Family Health and Human Reproduction Problems
Russian Federation

Oleg B. Ogarkov - Dr. Sci. (Med.), Scientific Centre for Family Health and Human Reproduction Problems.

664003, Irkutsk, Timiryazeva Str., 16.



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Review

For citations:


Orlova E.A., Kondratov I.G., Ogarkov O.B. COVID-19 Convalescents Exhibit Humoral Immunity to SARS-COV-2 Envelope (E) Protein. Journal Biomed. 2022;18(3):32-36. (In Russ.) https://doi.org/10.33647/2074-5982-18-3-32-36

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ISSN 2074-5982 (Print)
ISSN 2713-0428 (Online)