Adaptogenic and Neuroprotective Properties of Lithium Ascorbate
https://doi.org/10.33647/2074-5982-18-3-122-127
Abstract
In this work, we study the neuroprotective properties of lithium ascorbate in in vivo and in vitro stress models. Neurocytological and behavioral studies were carried out on models of stress in both a culture of nerve cells and experimental animals. The studied drug showed a significant neuroprotective effect of lithium ascorbate in neuronal cultures exposed to glutamate toxicity and an adaptogenic effect in stress models in rats. The results suggest that lithium ascorbate possess a high neuroprotective potential in stress models in vivo and in vitro.
About the Authors
K. S. Ostrenko
All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition — branch of the Federal Scientific Center of Animal Husbandry — The All-Russian Institute of Animal Husbandry named after Academician L.K. Ernst
Russian Federation
Russian Federation
Konstantin S. Ostrenko - Dr. Sci. (Biol.). All-Russian Research Institute of Physiology, Biochemistry and Animal Nutrition — branch of the Federal Scientific Center of Animal Husbandry — The All-Russian Institute of Animal Husbandry named after academician L.K. Ernst.
249013, Kaluga Region, Borovsk, Institut Village.
O. A. Gromova
Federal Research Center “Computer Science and Control” of the Russian Academy of Sciences
Russian Federation
Russian Federation
Olga A. Gromova - Dr. Sci. (Med.), Prof., Federal Research Center “Computer Science and Control” of the Russian Academy of Sciences.
119333, Moscow, Vavilova Str., 44/2.
V. V. Rastashansky
Normopharm
Russian Federation
Russian Federation
Vyacheslav V. Rastashansky.
121205, Moscow, terr. of the Innovation Center Skolkovo, Nobelya Str., 5.
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Review
For citations:
Ostrenko K.S., Gromova O.A., Rastashansky V.V. Adaptogenic and Neuroprotective Properties of Lithium Ascorbate. Journal Biomed. 2022;18(3):122-127. (In Russ.) https://doi.org/10.33647/2074-5982-18-3-122-127
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