Pharmaco-EEG Analysis of Regulatory Neuropeptides with Nootropic Properties in Cats
https://doi.org/10.33647/2074-5982-19-2-8-15
Abstract
Informative parameters of normalized electrograms of the brain of cats under the action of regulatory neuropeptides with nootropic properties were established using the example of the Semax drug. The results obtained were confirmed by a comparative pharmaco-EEG analysis with various pharmacological agents of directed action. The pronounced stable activating and nootropic effects of this pharmacological group in brain electrograms are distinguished by a unidirectional action that coincides with the data of pharmacodynamics and pharmacokinetics.
Keywords
About the Authors
Yu. V. Fokin
Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Yuriy V. Fokin - Cand. Sci. (Biol.), Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia.
143442, Moscow Region, Krasnogorsk District, Svetlye Gory Village, 1
S. Yu. Kharitonov
Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Sergey Yu. Kharitonov - Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia.
143442, Moscow Region, Krasnogorsk District, Svetlye Gory Village, 1
N. N. Karkischenko
Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia
Russian Federation
Russian Federation
Nikolay N. Karkischenko - Dr. Sci. (Med.), Prof., Academician of the Russian Academy of Rocket and Artillery Sciences, Corresponding Member of the RAS, Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia.
143442, Moscow Region, Krasnogorsk District, Svetlye Gory Village, 1
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Review
For citations:
Fokin Yu.V., Kharitonov S.Yu., Karkischenko N.N. Pharmaco-EEG Analysis of Regulatory Neuropeptides with Nootropic Properties in Cats. Journal Biomed. 2023;19(2):8-15. (In Russ.) https://doi.org/10.33647/2074-5982-19-2-8-15
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