Influence of a Nanoform of 9-phenyl-2,3,4,5,6,7,8,9-octahydro-1H-selenoxanthene on the Reproductive Function of White Rats
https://doi.org/10.33647/2713-0428-19-3E-85-89
Abstract
Despite the diversity of modern treatment methods, infertility rates remain high both in Russian and globally. In the present experimental study, we study the effect of a nanopreparation based on a selenoxanthene derivative and cyclodextrin on the reproduction of white outbred rats (females) after the administration of mifepristone. Selenoxanthene at a dose of 0.35 mg/kg and 0.7 mg/kg intragastrically for 5 days increased the reproductive activity of animals.
About the Authors
O. V. Buyuklinskayа
St. Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Olga V. Buyuklinskaya - Dr. Sci. (Med.), Assoc. Prof.
197376, St. Petersburg, Professora Popova str., 14, lit. A
S. M. Napalkova
St. Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Svetlana M. Napalkova - Dr. Sci. (Biol.), Prof.
197376, St. Petersburg, Professora Popova str., 14, lit. A
E. D. Kubasova
Northern State Medical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Elena D. Kubasova - Cand. Sci. (Biol.).
163000, Arkhangelsk, Troitskiy Ave., 51
D. S. Makarova
Maksavit
Russian Federation
Russian Federation
Daria S. Makarova – Maksavit.
163001, Arkhangelsk, Troitskiy Ave., 121/3
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Review
For citations:
Buyuklinskayа O.V., Napalkova S.M., Kubasova E.D., Makarova D.S. Influence of a Nanoform of 9-phenyl-2,3,4,5,6,7,8,9-octahydro-1H-selenoxanthene on the Reproductive Function of White Rats. Journal Biomed. 2023;19(3E):85-89. (In Russ.) https://doi.org/10.33647/2713-0428-19-3E-85-89
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