Differences in Models of Traumatic Brain Injury and the Subsequent Behavior Assessment in Rats and Mice
https://doi.org/10.33647/2074-5982-20-3-121-124
Abstract
Traumatic brain injury (TBI) is associated with varied and unpredictable consequences, which can be manifested during both acute and long-term periods. Such consequences may lead to the development of neurodegenerative diseases years and even decades after the injury. Given the heterogeneous nature of TBI in humans, preclinical studies need to be conducted using different test systems. Currently, preference is given to rodents due to their availability and low cost. However, the choice of test systems for research should be based not only on economic and logistical components, but also on their specific physiological characteristics.
About the Authors
S. A. Chervonetsky
Saint Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Sergey A. Chervonetsky
197376, Saint Petersburg, Professora Popova Str., 14, lit. A
A. A. Paimulina
Saint Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Alexandra A. Paimulina
197376, Saint Petersburg, Professora Popova Str., 14, lit. A
N. O. Selizarova
Saint Petersburg State Chemical and Pharmaceutical University of the Ministry of Health Care of Russia
Russian Federation
Russian Federation
Natalya O. Selizarova, Cand. Sci. (Med.), Assoc. Prof.
197376, Saint Petersburg, Professora Popova Str., 14, lit. A
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Review
For citations:
Chervonetsky S.A., Paimulina A.A., Selizarova N.O. Differences in Models of Traumatic Brain Injury and the Subsequent Behavior Assessment in Rats and Mice. Journal Biomed. 2024;20(3):121-124. (In Russ.) https://doi.org/10.33647/2074-5982-20-3-121-124
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