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Radiographic assessment delivery of powdery substances in broncho-pulmonary device of laboratory rat by "dry" insufflations

Abstract

In this research the technique of X-ray imaging of the respiratory department of outbred rats by administration of the contrast method "dry" insufflation was first tested. The usage of this method allows you to bring in a powdery substance in the broncho-pulmonary device rats up to the segmental bronchi fully, distributed evenly between the right and left lungs. The injection of barium sulphate (brought in dose of 100 mg) by the method of "dry" insufflation allows radiographic visualization of broncho-pulmonary device rats.

About the Authors

M. A. Syrtsova
ФГБУ «НИИ экспериментальной медицины» СЗО РАМН
Russian Federation


S. V. Okovitiy
НИЛ системного кровообращения Института экспериментальной медицины Северо-Западного федерального медицинского исследовательского центра МЗ РФ
Russian Federation


V. B. Bessonov
Санкт-Петербургский государственный электротехнический университет «ЛЭТИ» им. В.И. Ульянова (Ленина)
Russian Federation


M. V. Kotova
ГБОУ ВПО «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова»
Russian Federation


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Review

For citations:


Syrtsova M.A., Okovitiy S.V., Bessonov V.B., Kotova M.V. Radiographic assessment delivery of powdery substances in broncho-pulmonary device of laboratory rat by "dry" insufflations. Journal Biomed. 2016;(2):15-21. (In Russ.)

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ISSN 2074-5982 (Print)
ISSN 2713-0428 (Online)