Regeneration of pathologically changed liver of the carp after interspecific transplantation of stem cells

Abstract

One of ways of restoration of parenchymatous bodies at violations of various genesis is transplantation stem cells. The purpose of the real researches was studying of regeneration of a liver thresh a carp with artificially caused pathology under the influence of stem cells of donor mice. Fatty dystrophy of a liver of a carp was caused by 7-fold introduction of per os paracetamol in a dose of 15 g/kg. Experiment showed survival of stem cells of mice of donors in a liver threshes a carp and successful regeneration of body. It was confirmed with detection of a gene of green protein and the polymerase chain reaction (PCR), and also detection of the donor fluorescing cages in cryocuts of a liver thresh a carp and a hepatopancreas of crawfishes. Thus hydrobionts have an intensive regeneration of fabrics and a complete recovery of the struck bodies. Results of researches will allow expanding possibilities of transplantation of stem cells in development of medicobiological researches of in the vivo models in the field of cellular technologies.