Enteral administration of tributyrin as an element of nutritional support in the treatment of disruption of the intestinal electrical activity during experimental endotoxemia
Abstract
We investigated the electrical activity of the small intestine in rats intravenously administered 200 µg/kg of lipopolysaccharide E. coli . It has been shown that disturbances in the generation of migrating myoelectric complex were observed during the 96-hours after lipopolysaccharide administration. Enteral administration of tributyrin shortened overall recovery times migrating myoelectric complex to 48 hours.
About the Authors
E. A. Kislyakova
ГБУЗ г. Москвы «Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского Департамента здравоохранения г. Москвы»
Russian Federation
Russian Federation
N. S. Tropskaya
ГБУЗ г. Москвы «Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского Департамента здравоохранения г. Москвы»
Russian Federation
Russian Federation
T. S. Popova
ГБУЗ г. Москвы «Научно-исследовательский институт скорой помощи им. Н.В. Склифосовского Департамента здравоохранения г. Москвы»
Russian Federation
Russian Federation
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For citations:
Kislyakova E.A., Tropskaya N.S., Popova T.S. Enteral administration of tributyrin as an element of nutritional support in the treatment of disruption of the intestinal electrical activity during experimental endotoxemia. Journal Biomed. 2015;1(4):77-83. (In Russ.)
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