Evaluation of survival and safety of percutaneous osseointegrated implants made of various metal alloys

Abstract

In the work, an assessment was made of the survival and safety of the original percutaneous implant for the stump of a tubular bone made from different metal alloys. An experimental study was performed on male rabbits of the Chinchilla breed. The animals of the first group were implanted with a stainless steel product (grade EOS PH1), in the second group the implant was made of a titanium alloy (grade Ti6Al4V). Both implants are made by the additive technology of selective laser fusion by the method of layer-by-layer fusion of samples. The period of observation of the animals was 90 days after implantation. It was found that in animals of the first group two cases of implant prolapse were observed during the experiment, in the second group there were no such cases. In the first group there was one case of death of an animal, as well as three cases of chronic inflammation near the implant. With the same frequency, the animals of both groups showed an increase in the activity of transaminases and an increase in the level of the C-reactive protein. The results of the study showed that the survival rate and safety of a transdermal implant from a titanium alloy was higher relative to a product made of stainless steel.