Антагонистическая активность консорциума штаммов Lactobacillusfermentum ВКМ В-2793D и Lactobacillusreuteri ВКМ В-3144D, выделенных из женского молока, к мастит-индуцирующим патогенам

Целью работы явилось изучение антагонистической активности штаммов Lactobacillus fermentum BKM B-2793D, Lactobacillus reuteri BKM B-3144D, выделенных из женского молока, а также их консорциума к патогенам, вызывающим мастит в лактационный период. Установлено, что лактобактерии и их консорциум проявляют антагонистическую активность к индикаторным культурам, использованным в работе, включая резистентные к антибиотикам патогены. Консорциум обладает более выраженной антагонистической активностью к мастит-индуцирующим патогенам по сравнению с отдельными штаммами лактобактерий, входящими в его состав. Консорциум защищает клетки MCF-7 молочной железы человека от адгезии и колонизации патогеном S.aureus 8325-4. Полученные результаты свидетельствуют о том, что лактобактерии L.fermentum BKM B-2793D, L.reuteri BKM B-3144D, а также их консорциум являются отличными кандидатами для разработки пробиотического препарата для профилактики и лечения лактационного мастита.

лактобактерии женского молока, антагонистическая активность, биомоделирование

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