The influence of helium cold plasma on metabolic and physical-chemical parameters of human blood in vitro
Abstract
The aim of the study was comparative estimation of the changes of oxidative metabolism and crystallogenic properties of blood plasma under processing with cold helium plasma and non-ionized helium flow. We studied the influence of microwave-generating cold plasma on the specimens of whole human blood. The exposure time was 1 and 3 min. Before processing all blood specimens were divided into 5 portions. First portion was control (without any manipulations), second and third portion were treated with cold plasma, fourth and fifth ones were sparged with non-ionized helium flow. In all portions we estimated the parameters of oxidative metabolism and crystallogenic activity. It was stated that cold helium plasma and non-ionized helium modified these parameters under blood processing in vitro. For cold helium plasma this effect was realized by stimulation of antioxidant activity and crystallogenic properties of blood plasma. In opposite, non-ionized helium flow had prooxidant effect and demonstrated the inhibition of biological fluid crystallization. Our data showed that most optimal time for blood processing with cold plasma is 1 min.
About the Authors
A. K. Martusevich
ФГБУ «Приволжский федеральный медицинский исследовательский центр» Минздрава России, Нижний Новгород; Ассоциация российских озонотерапевтов
Russian Federation
Russian Federation
A. G. Soloveva
ФГБУ «Приволжский федеральный медицинский исследовательский центр» Минздрава России
Russian Federation
Russian Federation
S. Yu. Krasnova
ФГБУ «Приволжский федеральный медицинский исследовательский центр» Минздрава России
Russian Federation
Russian Federation
D. V. Yanin
ФГБУ «Приволжский федеральный медицинский исследовательский центр» Минздрава России
Russian Federation
Russian Federation
A. G. Galka
ФГБУ «Приволжский федеральный медицинский исследовательский центр» Минздрава России
Russian Federation
Russian Federation
A. V. Kostrov
ФИЦ «Институт прикладной физики РАН»
Russian Federation
Russian Federation
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54. Wiegand C., Fink S., Beier O., et al. Dose- and Time-Dependent Cellular Effects of Cold Atmospheric Pressure Plasma Evaluated in 3D Skin Models. Skin Pharmacol. Physiol. 2016. Vol. 29. Pp. 257-265.
Review
For citations:
Martusevich A.K., Soloveva A.G., Krasnova S.Yu., Yanin D.V., Galka A.G., Kostrov A.V. The influence of helium cold plasma on metabolic and physical-chemical parameters of human blood in vitro. Journal Biomed. 2018;(2):47-58. (In Russ.)
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